Pharmacokinetics Simulations
Elimination Rate Constant
PHARMACOKINETIC MODEL
The following shows the pharmacokinetic model for a single IV bolus dose - for a one compartment model. In this simulation, you will see how changes in k affect the plasma drug concentration.
Legend
Dose (D)
is the administered dose, mg. Preset and fixed at 1000mg.
Vd
is the volume of distribution, litres. Preset and fixed at 10 litres.
k
is the first order elimination rate constant, hour-1