Pharmacokinetics Simulations
Single Oral Dose
PHARMACOKINETIC MODEL
The following shows the pharmacokinetic model for a single oral dose - for a one compartment model. In this simulation, you will change the value of a single parameter at a time; all other parameters will be fixed.
Legend
Dose (D)
is the administered dose, mg
F
is the drug bioavailability, no units
Vd
is the volume of distribution, litres
ka
is the first order absorption rate constant, hour-1
k
is the elimination rate constant, hour-1