Pharmacokinetics Simulations
Single Oral Dose
DOSE
Larger doses result in higher plasma concentrations.
BIOAVAILABILITY
Higher drug bioavailability results in higher plasma concentrations.
ELIMINATION RATE CONSTANT
The larger the elimination rate constant, the faster the rate of drug elimination, leading to lower plasma concentrations.
ABSORPTION RATE CONSTANT
The larger the absorption rate constant, the faster the rate of drug absorption, leading to higher plasma concentrations.
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