INTRODUCTION

In this activity, you will be able to see how changes in four of the main parameters affect plasma drug concentration levels over time (the plasma drug concentration time profile). The parameters you can investigate here are:

The model used for the simulation is that of one compartment: single oral dose.

Page 2 shows the pharmacokinetic model for this simulation (also available by clicking on the option at the bottom left called "Pharmacokinetic Model"). The equations used are also available - click on "Equations" at the bottom left.