Agonists/Antagonists On Guinea Pig Ileum

A Single Combination Of Agonist And Antagonist

By using the experimental simulation in the next few pages, you can construct the dose-response curve for an agonist, and then construct dose-response curves for the agonist in the presence of several concentrations of an antagonist.

You will need to plan your experiment since you can only add eight amounts of the agonist and you need to obtain a good set of results so that a graph can be drawn.

Note the concentration of agonist being used as this will vary according to the concentration of antagonist chosen.

Comment On Experiment


Note: You can only see the results for ONE dose-response curve. If you wish to see the effect of the antagonist at several concentrations, you will need to write down your results and draw your own graphs.