Pharmacokinetics Simulations
One Compartment Model: Loading Dose And Multiple IV Bolus Doses
PHARMACOKINETIC MODEL
The following shows the pharmacokinetic model for multiple IV bolus doses with an initial loading dose - for a one compartment model.
Legend
Loading Dose (LD)
is the first administered dose if different from the following doses, mg
Dose (D)
is the administered dose, mg
Vd
is the volume of distribution, litres
k
is the elimination rate constant, hour-1
τ
is the dosage interval/time between doses, hours